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Guinea pig Drugs and Dosages

For additional information, review the Animal Use Training Handbook - Anesthesia/Analgesia Formulary

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GUINEA PIGS

Drug Dose (mg/kg) Route
PRE-ANESTHETIC MEDICATIONS
Atropine sulfate 0.02-0.05 IM, IV, SQ
SEDATIVES/TRANQUILIZERS
Acetylpromazine (Acepromazine´) 5-10 IM
Diazepam (Valium´) 2.5-5.0 IM, IP
Xylazine (Rompun´) 3-5 IM
Ketamine (Vetalar´, Ketaset´) 25-30 IM
INJECTABLE ANESTHETICS
Ketamine (Vetalar´, Ketaset´) 44-200 IM
Pentobarbital (Nembutal´) 25 IV
  28 IP
Thiopental (Pentothal´) 20 IV
  55 IP
Thiamylal (Surital´) 20 IV
ANESTHETIC COMBINATIONS
Ketamine and Xylazine 40 & 5.0 IM & SQ
Ketamine and Acepromazine 125 & 5.0 IM
Ketamine and Diazepam 100 & 5.0 IM
Ketamine, Xylazine and Acepromazine

Mix together 150 mg of 100 mg/ml [1.5 ml] ketamine, 30 mg of 20 mg/ml [1.5 ml] xylazine and 5 mg of 10 mg/ml [0.5 ml] Acepromazine

0.5-0.7 ml /kg IM, SQ
INHALATION ANESTHETICS Induction Maintenance
Methoxyflurane (Metofane´): No longer available.    
Fluothane (Halothane´) 1-3% 0.5-1.5%
Isoflourane (Aerrane´, Isoflo ´ ) up to 5% 2-3%
ANALGESICS
Nalbuphine (Nubain´) 1-2 IM, SQ q 6-8 h
Butorphanol (Torbutrol´, Stadol´) 0.025-0.40 IM, SQ q 4,6,8,12 h
Buprenorphine (Buprenex´) 0.05 SQ q 8-12 h
Meperidine (Demerol´) 10-20 SQ, IM q 2-3 h
Flunixin meglamine (Banamine´) 2.5-5 SQ q 12-24 h
Oxymorphan (Numorphan´ 0.2-0.5 SQ, IM q 6-12 h
Pentazocine (Talwin´) 10 SQ q 2-4 h
 NOT RECOMMENDED: Fentanyl & Droperidol (Innovar-Vet´), Ether, Chloroform

 

 
 
                     
                         
                         
 
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